Vysis® Prader-Willi/Angelman Region Probe - LSI® SNRPN SpectrumOrange/CEP® 15 (D15Z1) SpectrumGreen/LSI PML SpectrumOrangeTM

3765_4083
Prader-Willi/Angelman Region Probe - LSI SNRPN (SO)/CEP 15 (D15Z1) (SO)/LSI PML (SO)

Product Description

Probe Name Probe Location Fluorophore
Vysis LSI (D15Z1) 15p11.2  SpectrumGreen TM
Vysis LSI SNRPN 15q11-13  SpectrumOrange TM
Vysis LSI PML 15q22  SpectrumOrange TM
Four products are offered for the detection or characterization of abnormalities involving 15q11-q13. Vysis 15q11-q13 probes are premixed with a CEP 15 control probe. The SNRPN and D15S10 probe mixes also include LSI PML (15q22), a control probe useful for detecting rare translocations in AS and PWS.

Probe Map



Partial metaphase cell hybridized with LSI Prader-Willi/Angelman region (SNRPN) probe. Absence of orange-pink signal on one chromosome 15 indicates deletion of the SNRPN locus.

References

  1. Ozcelik, T. et. al. 1992. Nature Genetics 2; 265-269.
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Order Information

Product Name Package Size Vysis Order Number Abbott Order Number
Vysis Prader-Willi/Angelman Region Probe - LSI SNRPN (SO)/CEP 15 (D15Z1) (SO)/LSI PML (SO)  20 µL 32-190027 05J26-027
5J26
Analyte Specific Reagent.
Analytical and performance characteristics are not established.