Vysis® LSI® ZNF217 (20q13.2) SpectrumOrangeTM Probe
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis LSI ZNF217 | 20q13.2 | SpectrumOrange TM |
The LSI ZNF217 (20q13.2) Probe hybridizes within an approximately 1 Mb amplified segment within the 20q13.2 region. The LSI ZNF217 Probe contains the ZNF217 gene centrally located within this region of amplification. The ZNF217 gene is a candidate oncogene.Using the LSI ZNF217 probe, copy number or amplification of this region can be detected.
The LSI ZNF217 is an approximately 320 kb SpectrumOrange labeled probe.
The LSI ZNF217 is an approximately 320 kb SpectrumOrange labeled probe.
Probe Map
Results of Hybridization
When hybridized with the LSI ZNF217 Probe, a normal cell containing two copies of the 20q13.2 region will exhibit two orange signals. In a cell harboring amplification of the ZNF217 gene or 20q13.2 region, multiple copies of the orange signal will be observed.
LSI ZNF217 (20q13.2) SpectrumOrange hybridized to abnormal cells. Note multiple orange-pink signals contained within some cells indicate amplification of the ZNF217orange-pink signals contained within some cells indicate amplification of the ZNF217 locus.
References
- Tanner, M., et al. Cancer Res. 54 (16) (1994): 4257-4260.
- Collins, C., et al. Proc.Natl. Acad. Sci. USAVol. (1998): 8703-8708.
Analyte Specific Reagent.
Analytical and performance characteristics are not established.
Analytical and performance characteristics are not established.
