Vysis® LSI® TOP2A SpectrumOrangeTM / CEP® 17 SpectrumGreenTM Probe

20353_4623
LSI TOP2A SpectrumOrange/CEP 17 SpectrumGreen Probe

Product Description

Probe Name Probe Location Fluorophore
Vysis LSI TOP2A 17q21-22  SpectrumOrange TM
Vysis CEP 17 17p11.1-q11.1 Alpha Satellite DNA SpectrumGreen TM
This set is premixed in Hybridization Buffer.

Probe Map



Results of Hybridization


LSI TOP2A/CEP17 Dual-color Probe
In a cell with the normal quantity (two copies) of the TOP2A gene, two orange signals will be observed. If amplification or deletion of the TOP2A gene has occured, more or less than two signals will be present.

References

  1. Peng, J. et. al. 1988. Proc. Natl. Acad. Sci., USA; 85: 7177-81.
  2. Chen, AY. et. al. 1994. Annu rev Pharmacol Toxicol; 34: 191-218.
  3. Reca, J. 1994. Trends Biochem Sci; 20: 156-160.
  4. Capranico, G. 1990. Biochemistry; 29: 562-569.
  5. Schechter, AL. et. al. 1984. Nature; 312: 513-516.
  6. Slamon, DJ. et. al. 1989. Science; 244:707-712.
  7. Smith, K. et. al. 1993. Oncogene; 8: 933-938.
Back To Top

Order Information

Product Name Package Size Vysis Order Number Abbott Order Number
Vysis LSI TOP2A SpectrumOrange/CEP 17 SpectrumGreen Probe  200 µL 32-190095 05J55-001
5J55
Analyte Specific Reagent.
Analytical and performance characteristics are not established.