LSI® TCF3/PBX1 Dual Color, Dual Fusion Translocation Probe
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis® LSI TCF3 | 19p13.3 | SpectrumGreen TM |
| Vysis LSI PBX1 | 1q23 | SpectrumOrange TM |
Translocations occur between the TCF3 locus at chromosome 19p13.3 and the PBX1 locus at chromosome 1q23. The translocation event t(1;19)(q23;p13) produces a fusion of two genes on the derivative 19 chromosome that results in a novel chimeric gene, TCF3/PBX1.
The TCF3 SpectrumGreen probe is 730 kb in size and extends beyond the TCF3 gene to cover a larger region on chromosome 19p13.3. The PBX1 SpectrumOrange probe is 635 kb in size and covers the entire PBX1 gene on chromosome 1q23.
Please Note: No hybridization buffer included.
The TCF3 SpectrumGreen probe is 730 kb in size and extends beyond the TCF3 gene to cover a larger region on chromosome 19p13.3. The PBX1 SpectrumOrange probe is 635 kb in size and covers the entire PBX1 gene on chromosome 1q23.
Please Note: No hybridization buffer included.
Probe Map
Figure 1. Normal hybridization showing two orange and two green signals.
Figure 2. Example abnormal hybridization showing two orange, one green and one fusion signals.
