Vysis^® LSI^® N-MYC (2p24.1) SpectrumOrange^TM Probe

Product Description

Probe Name	Probe Location	Fluorophore
Vysis LSI N-MYC	2p24	SpectrumOrange ^TM

The LSI N-MYC (2p24.1) Probe contains unique DNA sequences specific to the N-MYC oncogene located within the 2p24.1 region of chromosome 2. This probe may be used to detect the N-MYC oncogene copy number.

The N-MYC (2p24.1) Probe is an approximately 200 kb SpectrumOrange labeled probe.

Probe Map

Results of Hybridization

In a normal cell, the expected pattern for a nucleus hybridized with the LSI N-MYC Probe is the two orange (2O) signal pattern. In an abnormal cell containing amplification of the N-MYC oncogene, greater than two orange signals will be observed.

LSI N-MYC Probe hybridized to a cell showing a high level of amplification of the N-MYC oncogene.

References

Heim, S., et al. Cancer Cytogenetics 2nd ed. (1995): 377.

Order Information

Product Name	Package Size	Vysis Order Number	Abbott Order Number
Vysis LSI N-MYC (2p24.1) SpectrumOrange Probe	20 µL	32-190013	05J50-001 5J50

Analyte Specific Reagent.
Analytical and performance characteristics are not established.