Vysis® LSI® D7S522 (7q31) SpectrumOrangeTM / CEP® 7 SpectrumGreenTM Probe
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis LSI D7S522 | 7q31 | SpectrumOrange TM |
| Vysis CEP 7 | 7p11.1-q11.1 | SpectrumGreen TM |
The LSI D7S522/CEP 7 Dual Color Probe may be used to identify deletions of 7q31 and to identify i(7q) in cells. A tumor suppressor gene is believed to be contained in the 7q31 region. The CEP 7 probe aids in determining if the deletion is of the whole chromosome 7 (-7) versus 7q-.
The LSI D7S522/CEP 7 Probe is a mixture of an approximately 200 kb SpectrumOrange labeled D7S522 and the CEP 7 labeled with SpectrumGreen.
The LSI D7S522/CEP 7 Probe is a mixture of an approximately 200 kb SpectrumOrange labeled D7S522 and the CEP 7 labeled with SpectrumGreen.
Probe Map
Results of Hybridization
In a normal cell hybridized with the LSI D7S522/CEP 7 Probe, the expected pattern is the two orange, two green (2O2G) signal pattern. In an abnormal cell containing the deletion, the one orange, two green (1O2G) signal pattern will be observed.
LSI D7S522/CEP 7 Dual Color Probe hybridized to a normal metaphase cell showing the two orange, two green (2O2G) signal pattern.
References
- Jenkins, R., et al. Cancer Research 58 (4) (1998): 759-66.
Analyte Specific Reagent.
Analytical and performance characteristics are not established.
Analytical and performance characteristics are not established.
