Vysis^® LSI^® 13 (RB1) 13q14 SpectrumOrange^TM Probe

Product Description

Probe Name	Probe Location	Fluorophore
Vysis LSI 13 (RB1)	13q14	SpectrumOrange ^TM

The LSI 13 (RB1) 13q14 SpectrumOrange Probe contains unique DNA sequences specific to the RB1 gene within the 13q14 region of chromosome 13. The presence or absence of the RB1 gene region may be detected using the LSI 13 (RB1) 13q14 Probe. This probe may be used to detect deletion (not mutation) of the RB1 gene locus.

The LSI 13 (RB1) 13q14 SpectrumOrange Probe is approximately 220 kb and contains sequences that target the entire RB1 gene.

Probe Map

Results of Hybridization

In a normal cell, the expected result for a nucleus hybridized with the LSI 13 (RB1) probe is a two orange (2O) signal pattern. In a hybridized abnormal cell containing the deletion, a one orange (1O) signal pattern will be observed.

LSI 13 (RB1) 13q14 Probe hybridized to a normal nucleus showing a two orange (2O) signal pattern.

References

Heim, S., et al. Cancer Cytogenetics 2nd ed. (1995): 377.

Order Information

Product Name	Status	Package Size	Vysis Order Number	Abbott Order Number
Vysis LSI 13 (RB1) 13q14 SpectrumOrange Probe	ASR	20 µL	32-190001	05J15-001 5J15
Vysis LSI 13 (RB1) 13q14 SpectrumOrange Probe		20 µL	32-160001	08L65-020 8L65

Analyte Specific Reagent.
Analytical and performance characteristics are not established.

CE Marked Not available in United States