Vysis 1p36 Microdeletion Region Probe - LSI p58 (1p36) (SpectrumOrange)/TelVysionTM 1p (SpectrumGreen)/LSI 1q25 (SpectrumAqua)
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis 1pTEL | 1pTEL | SpectrumGreen TM |
| Vysis LSI P58 | 1p36 | SpectrumOrange TM |
| Vysis LSI 1q25 | 1q25 | SpectrumAqua TM |
Terminal deletions involving the 1p subtelomere region and interstitial deletions of 1p36, as well as derivative chromosomes and complex rearrangements resulting in monosomy 1p36, are targeted with this probe set.
The 1p36 Microdeletion Probe Set includes FISH probes to the 1p subtelomere region labeled in SpectrumGreen, p58 (CDC2L1) within 1p36 labeled in SpectrumOrange, and a control probe on 1q25 labeled in SpectrumAqua.
The 1p36 Microdeletion Probe Set includes FISH probes to the 1p subtelomere region labeled in SpectrumGreen, p58 (CDC2L1) within 1p36 labeled in SpectrumOrange, and a control probe on 1q25 labeled in SpectrumAqua.
Probe Map
1p36 Microdeletion Probe hybridized to a metaphase cell.
References
- Heilstedt HA et al., Population data suggest that deletions of 1p36 are a relatively common chromosome abnormality. Clin Genet 64:310-316, 2003.
- Heilstedt HA et al., Physical map of 1p36, placement of monosomy 1p36, and clinical characterization of the syndrome. Am J Hum Genet 72:1200-1212, 2003.
Analyte Specific Reagent.
Analytical and performance characteristics are not established.
Analytical and performance characteristics are not established.
